You are here: Home The Group Benedikt Sohmen

Benedikt Sohmen

Benedikt SohmenPhD student


Institute of Physical Chemistry

Albertstraße 23 a

79104 Freiburg


Phone: +49 761 203-6186

Room:  2004, 2nd floor




Single-molecule studies on the dynamic structure of complex multi-domain proteins

•    Understanding of the molecular chaperone Hsp90

o    Why is Hsp90 a central key regulator in our cells?
o    How does Hsp90 trigger vital cellular signal pathways?
o    How is the human kinome activated by Hsp90?
•    Protein expression, production & purification

•    Site-specific fluorescent labelling of proteins

•    Confocal single-molecule measurements

•    Matlab smFRET data analysis


4F-TIRF_ES Histo 


 “There is plenty of room at the bottom” Richard Feynman 1959

60 years after Richard Feynman’s vision, we really “see” and begin to understand the world of nano, including complex single biomolecules and molecular machines. For me that’s amazing.