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Benedikt Sohmen

Benedikt SohmenPhD student

 

Institute of Physical Chemistry

Albertstraße 23 a

79104 Freiburg

 

Phone: +49 761 203-6186

Room:  2004, 2nd floor

Email:  benedikt.sohmen@physchem.uni-freiburg.de

 

Research

Single-molecule studies on the dynamic structure of complex multi-domain proteins

•    Understanding of the molecular chaperone Hsp90

o    Why is Hsp90 a central key regulator in our cells?
o    How does Hsp90 trigger vital cellular signal pathways?
o    How is the human kinome activated by Hsp90?
 
•    Protein expression, production & purification

•    Site-specific fluorescent labelling of proteins

•    Confocal single-molecule measurements

•    Matlab smFRET data analysis

 

4F-TIRF_ES Histo 

 
 

 “There is plenty of room at the bottom” Richard Feynman 1959


60 years after Richard Feynman’s vision, we really “see” and begin to understand the world of nano, including complex single biomolecules and molecular machines. For me that’s amazing.