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Mathäus Tschaikowsky

TschaikowskyPhD student / Doktorand


Institute of Physical Chemistry

Albertstraße 23 a

79104 Freiburg


Phone: +49 761 203-6173
Fax:     +49 761 203-6189

Room:  2006, 2nd floor




Osteoarthritis is a major burden for patients and health care systems and still the most common cause of disability. In cooperation with G.E.R.N. lab (Universitätsklinikum Freiburg) we study the nanomechanical and morphological changes in human cartilage at the early stages of disease. Using Atomic Force Microscopy (AFM) in combination with fluorescence microscopy we are gaining insights into the pathology of the tissue on a nanometer scale.




About me:

  • 07/19: Alumni award of the Faculty of Chemistry and Pharmacy, Albert-Ludwigs-Universität Freiburg
  • since 11/2018: PhD student in the Hugel Group
  • 10/18: MSc Biochemistry and Biophysics (very good with honors), Albert-Ludwigs-Universität Freiburg                          Topic: Nanomechanical properties of human osteoarthritic cartilage
    AK Prof. Dr. Hugel and AG Prof. Dr. Bernd Rolauffs (G.E.R.N. lab)
  • 10/16: BSc Chemistry, Albert-Ludwigs-Universität Freiburg and ETH Zürich



  • Tschaikowsky, M., Brander, S., Balzer, B. N., Rolauffs, B., & Hugel, T.
    Proof-of-concept for the detection of early osteoarthritis pathology by endomicroscopy
    bioRxiv, 734368 (2019)
  • Tschaikowsky, M., Brander, S., Balzer, B. N., Rolauffs, B. and Hugel, T. (2019). Detection of early stage human osteoarthritis by local cartilage surface nanoscale stiffness and chondrocyte spatial organization. Manuscript submitted for publication.



  • 07/19: Poster award for “Towards a mechanistic understanding and detection of early-onset osteoarthritis” (Tag der Forschung, Freiburg)